.patients-page {
    --patients-curve-height: clamp(150px, 13vw, 220px);
    --patients-gutter: 1.5625rem;
    --patients-page-gutter: var(--patients-gutter);
    --patients-azenosertib-media-max: 21.5rem;
    --patients-more-choice-media-max: 26.6875rem;
    --patients-azenosertib-block-top: 97px;
    --patients-azenosertib-block-bottom: 38px;
    overflow-x: hidden;
}

@media (max-width: 840px) {
    .patients-page {
        --patients-azenosertib-block-top: 29px;
    }
}

.patients-page .two-columns-with-image .container {
    max-width: 67.3125rem;
}

.patients-page > section:not(.patients-page__section-row) {
    padding-left: var(--patients-gutter);
    padding-right: var(--patients-gutter);
}

.patients-page__section-row > div:not(.moa-graphic) {
    padding-left: var(--patients-gutter);
    padding-right: var(--patients-gutter);
}

.patients-page__section-row > div > .container {
    padding-left: 0;
    padding-right: 0;
}

.hero-section.hero-section--patients {
    padding-top: 100px;
    padding-bottom: 130px;
    position: relative;
    z-index: 2;
    text-align: center;
}

.hero-section.hero-section--patients .container {
    position: relative;
    z-index: 1;
}

.hero-section.hero-section--patients::after {
    content: "";
    position: absolute;
    left: 0;
    right: 0;
    bottom: -1px;
    height: var(--patients-curve-height);
    background: url("../images/blue-top-curve.svg") top center / 100% auto no-repeat;
    pointer-events: none;
    z-index: 0;
}

.hero-section.hero-section--patients .hero-section__headline {
    color: var(--Primary-Blue, #021F90);
    text-align: center;
    text-transform: lowercase;
    font-family: "DM Serif Display";
    font-size: 3.75rem;
    font-style: normal;
    font-weight: 400;
    line-height: 88%;
    margin: 0 0 10px;
}

.hero-section.hero-section--patients .hero-section__headline .dot {
    color: #FF2E83;
}

.hero-section.hero-section--patients .hero-section__subtext {
    color: #0C9ECF;
    text-align: center;
    font-family: "DM Sans";
    font-size: 1.125rem;
    font-style: normal;
    font-weight: 500;
    line-height: 140%;
    letter-spacing: 0.12375rem;
    text-transform: uppercase;
    margin: 0 auto 24px;
    max-width: 90%;
}

.hero-section.hero-section--patients .hero-section__bottom-text {
    color: #313134;
    font-size: 21px;
    font-weight: 400;
    line-height: 36px;
    margin: 0 auto;
    max-width: 860px;
}

.hero-section.hero-section--patients .hero-section__bottom-text > *:first-child {
    margin-top: 0;
}

.patients-page__content {
    padding-top: 120px;
    padding-bottom: 80px;
}

.patients-page__content--after-hero {
    padding-top: 40px;
}

.patients-page__content--patients {
    background: #021F90;
    color: #fff;
    position: relative;
    z-index: 1;
}

.patients-page__content--patients.patients-page__content--after-hero {
    padding-top: 160px;
}

.patients-page__content--patients .container {
    position: relative;
    z-index: 2;
}

.patients-page .two-columns-with-image {
    padding-top: 80px;
    padding-bottom: 80px;
}

.two-columns-with-image--patients,
.two-columns-with-image--more-choice,
.two-columns-image--more-choice {
    color: #fff;
    position: relative;
    z-index: 1;
}

.two-columns-with-image--patients .container,
.two-columns-with-image--more-choice .container,
.two-columns-image--more-choice .container {
    position: relative;
    z-index: 2;
}

.two-columns-with-image--more-choice,
.two-columns-image--more-choice {
    background: var(--Primary-Blue, #021F90);
    padding-top: 80px;
    padding-bottom: 80px;
}

.two-columns-with-image--patients {
    background: var(--Primary-Blue, #021F90);
    padding-top: 80px;
    padding-bottom: 80px;
}

.patients-page__content--patients .two-columns-with-image__inner,
.two-columns-with-image--patients .two-columns-with-image__inner,
.two-columns-with-image--more-choice .two-columns-with-image__inner,
.two-columns-image--more-choice .two-columns-with-image__inner {
    display: flex;
    justify-content: space-between;
    gap: 64px;
}

.patients-page__content--patients .two-columns-with-image--image-left .two-columns-with-image__inner,
.two-columns-with-image--patients.two-columns-with-image--image-left .two-columns-with-image__inner,
.two-columns-with-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__inner,
.two-columns-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__inner {
    flex-direction: row-reverse;
}

.patients-page__content--patients .two-columns-with-image__content,
.two-columns-with-image--patients .two-columns-with-image__content,
.two-columns-with-image--more-choice .two-columns-with-image__content,
.two-columns-image--more-choice .two-columns-with-image__content {
    flex: 1 1 52%;
    min-width: 0;
}

.patients-page__content--patients .two-columns-with-image__media,
.two-columns-with-image--patients .two-columns-with-image__media,
.two-columns-with-image--more-choice .two-columns-with-image__media,
.two-columns-image--more-choice .two-columns-with-image__media {
    flex: 0 0 42%;
    position: relative;
}

.patients-page__content--patients .two-columns-with-image__media::after,
.two-columns-with-image--patients .two-columns-with-image__media::after,
.two-columns-with-image--more-choice .two-columns-with-image__media::after,
.two-columns-image--more-choice .two-columns-with-image__media::after {
    content: "";
    position: absolute;
    top: 0;
    right: -70px;
    width: 55%;
    height: 100%;
    background: #8C037B;
    z-index: 0;
}

.two-columns-with-image--more-choice .two-columns-with-image__media::after,
.two-columns-image--more-choice .two-columns-with-image__media::after {
    top: -43px;
    left: 247px;
    right: calc(50% - 50vw);
    width: auto;
    height: 461px;
    background: linear-gradient(21deg, #670D7C -1.04%, #95007F 100%);
}

.patients-page__content--patients .two-columns-with-image__media-inner,
.two-columns-with-image--patients .two-columns-with-image__media-inner,
.two-columns-with-image--more-choice .two-columns-with-image__media-inner,
.two-columns-image--more-choice .two-columns-with-image__media-inner {
    position: relative;
    z-index: 1;
    background: #fff;
    padding: 8px;
}

.two-columns-with-image--more-choice .container,
.two-columns-image--more-choice .container {
    max-width: 67.3125rem;
}

.patients-page__content--patients .two-columns-with-image__image,
.two-columns-with-image--patients .two-columns-with-image__image,
.two-columns-with-image--more-choice .two-columns-with-image__image,
.two-columns-image--more-choice .two-columns-with-image__image {
    width: 100%;
    height: auto;
    display: block;
    border-radius: 0 80px;
}

.two-columns-with-image--more-choice .two-columns-with-image__media,
.two-columns-image--more-choice .two-columns-with-image__media {
    flex: 0 0 427px;
}

.two-columns-with-image--more-choice .two-columns-with-image__media-inner,
.two-columns-image--more-choice .two-columns-with-image__media-inner {
    background: transparent;
    padding: 0;
}

.two-columns--azenosertib .container {
    max-width: 67.3125rem;
}

.two-columns-image--azenosertib-works .container {
    max-width: 67.3125rem;
}

.two-columns--azenosertib {
    background: #fff;
    color: #313134;
}

.two-columns-image--azenosertib-works {
    background: #fff;
    color: #313134;
}

.two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__inner {
    display: flex;
    flex-direction: column;
    align-items: stretch;
}

.two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__inner {
    display: flex;
    flex-direction: column;
    align-items: stretch;
}

.two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__headline {
    color: var(--Primary-Blue, #021F90);
    font-family: "DM Serif Display";
    font-size: 3.75rem;
    font-style: normal;
    font-weight: 400;
    line-height: 104%;
    margin: 0 0 40px;
    text-align: center;
}

.two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__headline .dot {
    color: var(--Secondary-Pink, #FF2E83);
}

.two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__headline {
    color: var(--Primary-Blue, #021F90);
    font-family: "DM Serif Display";
    font-size: 3.75rem;
    font-style: normal;
    font-weight: 400;
    line-height: 104%;
    margin: 0 0 30px;
    text-align: center;
}

.two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__headline .dot {
    color: var(--Secondary-Pink, #FF2E83);
}

.two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__columns {
    display: flex;
    gap: 53px;
    justify-content: flex-start;
    align-items: flex-start;
}

.two-columns--azenosertib.two-columns-with-image--image-left .two-columns-with-image__media {
    order: -1;
}

.two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__columns {
    display: flex;
    gap: 50px;
    justify-content: flex-start;
    align-items: flex-start;
}

.two-columns-image--azenosertib-works .two-columns-with-image__media {
    order: -1;
}

.two-columns--azenosertib .two-columns-with-image__content {
    flex: 0 1 626px;
    max-width: 626px;
}

.two-columns-image--azenosertib-works .two-columns-with-image__content {
    flex: 0 1 626px;
    max-width: 626px;
}

.two-columns--azenosertib .two-columns-with-image__text {
    color: #313134;
    font-family: "DM Sans";
    font-size: 1.3125rem;
    font-style: normal;
    font-weight: 400;
    line-height: 2.25rem;
    margin-bottom: 0;
}

.two-columns-image--azenosertib-works .two-columns-with-image__text {
    color: #313134;
    font-family: "DM Sans";
    font-size: 1.3125rem;
    font-style: normal;
    font-weight: 400;
    line-height: 2.25rem;
    margin-bottom: 0;
}

.two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__media {
    flex: 0 0 344px;
    width: 344px;
    height: 334px;
    position: relative;
    z-index: 0;
}

.two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__media {
    flex: 0 0 344px;
    width: 344px;
    height: 334px;
    position: relative;
    z-index: 0;
}

.two-columns--azenosertib.two-columns-with-image--image-left .two-columns-with-image__media::after {
    content: "";
    position: absolute;
    top: calc(-1 * var(--patients-azenosertib-block-top));
    /*
     * Keep the decorative block flush with the viewport edge:
     * - up to the 1077px content width breakpoint, use the fixed section gutter
     * - beyond that, use the centered container offset
     */
    left: calc(-1 * max(var(--patients-gutter), calc(50vw - 33.65625rem)));
    right: 148px;
    bottom: calc(-1 * var(--patients-azenosertib-block-bottom));
    background: linear-gradient(28deg, var(--Secondary-Blue, #0C9ECF) 5.47%, var(--Secondary-Blue, #39C6F4) 76.22%);
    z-index: 0;
    pointer-events: none;
}

.two-columns-image--azenosertib-works.two-columns-with-image--image-left .two-columns-with-image__media::after {
    content: "";
    position: absolute;
    top: calc(-1 * var(--patients-azenosertib-block-top));
    left: calc(-1 * max(var(--patients-gutter), calc(50vw - 33.65625rem)));
    right: 148px;
    bottom: calc(-1 * var(--patients-azenosertib-block-bottom));
    background: linear-gradient(28deg, var(--Secondary-Blue, #0C9ECF) 5.47%, var(--Secondary-Blue, #39C6F4) 76.22%);
    z-index: 0;
    pointer-events: none;
}

.two-columns--azenosertib .two-columns-with-image__media-inner {
    position: relative;
    background: transparent;
    padding: 0;
    z-index: 1;
}

.two-columns-image--azenosertib-works .two-columns-with-image__media-inner {
    position: relative;
    background: transparent;
    padding: 0;
    z-index: 1;
}

.two-columns--azenosertib .two-columns-with-image__image {
    position: relative;
    z-index: 1;
    width: 344px;
    height: 334px;
    object-fit: cover;
    border-radius: 80px 0;
}

.two-columns-image--azenosertib-works .two-columns-with-image__image {
    position: relative;
    z-index: 1;
    width: 344px;
    height: 334px;
    object-fit: cover;
    border-radius: 80px 0;
}

.two-columns-with-image--more-choice .two-columns-with-image__image,
.two-columns-image--more-choice .two-columns-with-image__image {
    width: 427px;
    height: 468px;
    object-fit: cover;
}

@media (max-width: 68.75rem) and (min-width: 62.0625rem) {
    /*
     * 993px-1100px:
     * Reduce the azenosertib media footprint so the two-column row
     * does not force horizontal overflow before the mobile/tablet stack kicks in.
     */
    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__columns,
    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__columns {
        gap: 2rem;
    }

    .two-columns--azenosertib .two-columns-with-image__content,
    .two-columns-image--azenosertib-works .two-columns-with-image__content {
        flex: 1 1 auto;
        max-width: none;
        min-width: 0;
    }

    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__media,
    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__media {
        flex: 0 0 18.75rem;
        width: 18.75rem;
        height: auto;
    }

    .two-columns--azenosertib .two-columns-with-image__image,
    .two-columns-image--azenosertib-works .two-columns-with-image__image {
        width: 100%;
        height: auto;
    }

    .two-columns--azenosertib.two-columns-with-image--image-left .two-columns-with-image__media::after,
    .two-columns-image--azenosertib-works.two-columns-with-image--image-left .two-columns-with-image__media::after {
        right: 9.75rem;
    }
}

@media (max-width: 62rem) and (min-width: 40.0625rem) {
    .two-columns-with-image--more-choice .two-columns-with-image__inner,
    .two-columns-image--more-choice .two-columns-with-image__inner {
        flex-direction: row;
        align-items: center;
        gap: 2rem;
    }

    .two-columns-with-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__inner,
    .two-columns-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__inner {
        flex-direction: row-reverse;
    }

    .two-columns-with-image--more-choice .two-columns-with-image__media,
    .two-columns-image--more-choice .two-columns-with-image__media {
        flex: 0 0 18.75rem;
        width: 18.75rem;
        max-width: 18.75rem;
        margin-right: 0;
    }

    .two-columns-with-image--more-choice .two-columns-with-image__image,
    .two-columns-image--more-choice .two-columns-with-image__image {
        width: 100%;
        height: auto;
    }

    .two-columns-with-image--more-choice .two-columns-with-image__media::after,
    .two-columns-image--more-choice .two-columns-with-image__media::after {
        left: 57.85%;
        right: calc(50% - 50vw);
    }

    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__columns,
    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__columns {
        flex-direction: row;
        align-items: flex-start;
        gap: 2rem;
    }

    .two-columns--azenosertib .two-columns-with-image__content,
    .two-columns-image--azenosertib-works .two-columns-with-image__content {
        flex: 1 1 auto;
        max-width: none;
        min-width: 0;
    }

    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__media,
    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__media {
        flex: 0 0 16.25rem;
        width: 16.25rem;
        max-width: 16.25rem;
        height: auto;
    }

    .two-columns--azenosertib .two-columns-with-image__image,
    .two-columns-image--azenosertib-works .two-columns-with-image__image {
        width: 100%;
        height: auto;
    }

    .two-columns--azenosertib.two-columns-with-image--image-left .two-columns-with-image__media::after,
    .two-columns-image--azenosertib-works.two-columns-with-image--image-left .two-columns-with-image__media::after {
        right: 7rem;
    }
}

@media (max-width: 60rem) and (min-width: 40.0625rem) {
    .two-columns--azenosertib.two-columns-with-image--image-left .two-columns-with-image__media::after,
    .two-columns-image--azenosertib-works.two-columns-with-image--image-left .two-columns-with-image__media::after {
        right: 10.125rem;
    }
}

@media (max-width: 40rem) {
    .patients-page {
        --patients-azenosertib-block-top: 97px;
    }

    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__columns {
        flex-direction: column;
        align-items: stretch;
    }

    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__columns {
        flex-direction: column;
        align-items: stretch;
    }

    .two-columns--azenosertib.two-columns-with-image--image-left .two-columns-with-image__media,
    .two-columns-image--azenosertib-works .two-columns-with-image__media {
        order: 0;
    }

    .two-columns--azenosertib .two-columns-with-image__content,
    .two-columns-image--azenosertib-works .two-columns-with-image__content {
        flex: 1 1 auto;
        max-width: none;
        min-width: 0;
        margin-bottom: 100px;
    }

    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__media {
        width: 100%;
        max-width: 344px;
        height: auto;
    }

    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__media {
        width: 100%;
        max-width: 344px;
        height: auto;
    }

    .two-columns--azenosertib .two-columns-with-image__image {
        width: 100%;
        height: auto;
    }

    .two-columns-image--azenosertib-works .two-columns-with-image__image {
        width: 100%;
        height: auto;
    }

    .two-columns--azenosertib .two-columns-with-image__media::after {
        left: calc(-1 * var(--patients-gutter));
        right: 96px;
        top: calc(-1 * var(--patients-azenosertib-block-top));
        bottom: calc(-1 * var(--patients-azenosertib-block-bottom));
        height: auto;
    }

    .two-columns-image--azenosertib-works .two-columns-with-image__media::after {
        left: calc(-1 * var(--patients-gutter));
        right: 96px;
        top: calc(-1 * var(--patients-azenosertib-block-top));
        bottom: calc(-1 * var(--patients-azenosertib-block-bottom));
        height: auto;
    }
}

.two-columns-with-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__media::after,
.two-columns-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__media::after {
    left: 247px;
    right: calc(50% - 50vw);
}

.patients-page__content--patients .two-columns-with-image__headline,
.two-columns-with-image--patients .two-columns-with-image__headline,
.two-columns-with-image--more-choice .two-columns-with-image__headline,
.two-columns-image--more-choice .two-columns-with-image__headline {
    color: var(--Neutral-White, #FFF);
    font-family: "DM Serif Display";
    font-size: 3.75rem;
    font-style: normal;
    font-weight: 400;
    line-height: 110%;
    margin: 0 0 20px;
}

.two-columns-image--more-choice.two-columns-with-image--image-right .two-columns-with-image__headline {
    text-wrap: balance;
}

.patients-page__content--patients .two-columns-with-image__headline .dot,
.two-columns-with-image--patients .two-columns-with-image__headline .dot,
.two-columns-with-image--more-choice .two-columns-with-image__headline .dot,
.two-columns-image--more-choice .two-columns-with-image__headline .dot {
    color: #FF2E83;
}

.patients-page__content--patients .two-columns-with-image__text,
.two-columns-with-image--patients .two-columns-with-image__text,
.two-columns-with-image--more-choice .two-columns-with-image__text,
.two-columns-image--more-choice .two-columns-with-image__text {
    color: var(--Neutral-White, #FFF);
    font-family: "DM Sans";
    font-size: 1.3125rem;
    font-style: normal;
    font-weight: 400;
    line-height: 2.25rem;
    max-width: 520px;
    margin-bottom: 20px;
}

.patients-page__content--patients .two-columns-with-image__text > *:first-child,
.two-columns-with-image--patients .two-columns-with-image__text > *:first-child,
.two-columns-with-image--more-choice .two-columns-with-image__text > *:first-child,
.two-columns-image--more-choice .two-columns-with-image__text > *:first-child {
    margin-top: 0;
}

.patients-page__content--patients .two-columns-with-image__button,
.two-columns-with-image--patients .two-columns-with-image__button,
.two-columns-with-image--more-choice .two-columns-with-image__button,
.two-columns-image--more-choice .two-columns-with-image__button {
    display: inline-flex;
    align-items: center;
    gap: 10px;
    color: #fff;
    font-family: "DM Sans";
    font-size: 0.875rem;
    font-weight: 500;
    text-decoration: none;
    padding: 8px 14px;
    border-radius: 999px;
    border: 1px solid rgba(255, 255, 255, 0.55);
}

.two-columns-with-image--more-choice .two-columns-with-image__button,
.two-columns-image--more-choice .two-columns-with-image__button {
    display: inline-flex;
    padding: 10px 12px 10px 10px;
    align-items: center;
    gap: 12px;
    border-radius: 100px;
    background: var(--Neutral-White, #FFF);
    border: 0;
    color: #511861;
    width: fit-content;
    max-width: max-content;
    font-family: "DM Sans";
    font-size: 1.3125rem;
    font-style: normal;
    font-weight: 500;
    line-height: 1.0625rem;
}

.two-columns-with-image--more-choice .two-columns-with-image__button-icon,
.two-columns-image--more-choice .two-columns-with-image__button-icon {
    width: 20px;
    height: 20px;
    aspect-ratio: 1 / 1;
    display: block;
    flex: 0 0 auto;
}

.two-columns-with-image--more-choice .two-columns-with-image__button-icon--hover,
.two-columns-image--more-choice .two-columns-with-image__button-icon--hover {
    display: none;
}

.patients-page__content--patients .two-columns-with-image__button:hover,
.two-columns-with-image--patients .two-columns-with-image__button:hover,
.two-columns-with-image--more-choice .two-columns-with-image__button:hover,
.two-columns-image--more-choice .two-columns-with-image__button:hover {
    border-color: rgba(255, 255, 255, 0.85);
}

.two-columns-with-image--more-choice .two-columns-with-image__button:hover,
.two-columns-image--more-choice .two-columns-with-image__button:hover {
    border-color: transparent;
    color: var(--Primary-Light-Magenta, #AC1AB8);
    opacity: 1;
}

.two-columns-with-image--more-choice .two-columns-with-image__button:hover .two-columns-with-image__button-icon--default,
.two-columns-image--more-choice .two-columns-with-image__button:hover .two-columns-with-image__button-icon--default {
    display: none;
}

.two-columns-with-image--more-choice .two-columns-with-image__button:hover .two-columns-with-image__button-icon--hover,
.two-columns-image--more-choice .two-columns-with-image__button:hover .two-columns-with-image__button-icon--hover {
    display: block;
}

@media (max-width: 40rem) {
    .two-columns-with-image--more-choice .two-columns-with-image__image,
    .two-columns-image--more-choice .two-columns-with-image__image {
        width: 21.75rem;
        max-width: 100%;
        height: auto;
    }

    .patients-page__content--patients .two-columns-with-image__inner,
    .two-columns-with-image--patients .two-columns-with-image__inner,
    .two-columns-with-image--more-choice .two-columns-with-image__inner,
    .two-columns-image--more-choice .two-columns-with-image__inner {
        flex-direction: column;
        align-items: stretch;
    }

    .patients-page__content--patients .two-columns-with-image--image-left .two-columns-with-image__inner,
    .two-columns-with-image--patients.two-columns-with-image--image-left .two-columns-with-image__inner,
    .two-columns-with-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__inner,
    .two-columns-image--more-choice.two-columns-with-image--image-left .two-columns-with-image__inner {
        flex-direction: column;
    }

    .patients-page__content--patients .two-columns-with-image__media,
    .two-columns-with-image--patients .two-columns-with-image__media,
    .two-columns-with-image--more-choice .two-columns-with-image__media,
    .two-columns-image--more-choice .two-columns-with-image__media {
        max-width: 520px;
    }

    .two-columns-with-image--more-choice .two-columns-with-image__media,
    .two-columns-image--more-choice .two-columns-with-image__media {
        align-self: flex-end;
        width: min(100%, 21.75rem);
        max-width: 21.75rem;
        margin-right: 0;
    }

    .two-columns-with-image--more-choice .two-columns-with-image__media-inner,
    .two-columns-image--more-choice .two-columns-with-image__media-inner {
        margin-left: auto;
        margin-right: 0;
    }

    .patients-page__content--patients .two-columns-with-image__media::after,
    .two-columns-with-image--patients .two-columns-with-image__media::after,
    .two-columns-with-image--more-choice .two-columns-with-image__media::after,
    .two-columns-image--more-choice .two-columns-with-image__media::after {
        right: calc(-1 * var(--patients-gutter));
    }

    .two-columns-with-image--more-choice .two-columns-with-image__media::after,
    .two-columns-image--more-choice .two-columns-with-image__media::after {
        right: calc(-1 * var(--patients-gutter));
    }
}

.patients-page__top-curve {
    position: absolute;
    top: 0;
    left: 0;
    width: 100%;
    overflow: hidden;
    line-height: 0;
    height: var(--patients-curve-height, 185px);
    z-index: 1;
    pointer-events: none;
}

.patients-page__top-curve img {
    display: block;
    width: 100%;
    height: auto;
}

.patients-page__content h1 {
    margin: 0 0 24px;
}

.patients-page__body > *:first-child {
    margin-top: 0;
}

.three-box-content--patients {
    position: relative;
    background: #fff;
    padding-bottom: 80px;
}

.three-box-content--patients::before {
    content: "";
    position: absolute;
    top: -1px;
    left: 0;
    right: 0;
    aspect-ratio: 1920 / 255;
    height: auto;
    background: url("../images/blue-bottom-curve.svg") bottom center / 100% auto no-repeat;
    z-index: 0;
    pointer-events: none;
}

.three-box-content--patients .container {
    position: relative;
    z-index: 1;
}

.three-box-content--patients .three-box-content__headline {
    font-family: "DM Sans";
    font-size: 1.125rem;
    font-style: normal;
    font-weight: 500;
    line-height: 140%;
    letter-spacing: 0.12375rem;
    text-transform: uppercase;
}

.three-box-content--patients .three-box-content__box:nth-child(1) .three-box-content__headline {
    color: var(--Secondary-Pink, #FF2E83);
}

.three-box-content--patients .three-box-content__box:nth-child(2) .three-box-content__headline {
    color: var(--Secondary-Blue, #0C9ECF);
}

.three-box-content--patients .three-box-content__box:nth-child(3) .three-box-content__headline {
    color: var(--Secondary-Green, #00A870);
}

.three-box-content--patients .three-box-content__grid {
    display: flex;
    gap: 39px;
    justify-content: center;
    align-items: stretch;
    flex-wrap: wrap;
}

.three-box-content--patients .three-box-content__box {
    display: flex;
    width: 366px;
    padding: 13px 37px 23px 37px;
    justify-content: center;
    align-items: center;
    flex-direction: column;
    border-radius: 0 40px;
    border-top: 10px solid var(--Secondary-Pink, #FF2E83);
    background: var(--Neutral-White, #FFF);
    box-shadow: 0 4px 19px 0 rgba(0, 0, 0, 0.07);
}

.three-box-content--patients .three-box-content__box:nth-child(2) {
    border-top-color: var(--Secondary-Blue, #0C9ECF);
}

.three-box-content--patients .three-box-content__box:nth-child(3) {
    border-top-color: var(--Secondary-Green, #00A870);
}

.three-box-content--patients .three-box-content__headline,
.three-box-content--patients .three-box-content__text {
    width: 100%;
    text-align: left;
}

@media (max-width: 420px) {
    .three-box-content--patients .three-box-content__box {
        width: 100%;
        padding-left: 24px;
        padding-right: 24px;
    }
}

@media (max-width: 50.625rem) {
    .three-box-content--patients .three-box-content__grid {
        flex-wrap: wrap;
        justify-content: center;
    }

    .three-box-content--patients .three-box-content__box {
        flex: 0 1 calc((100% - 2.4375rem) / 2);
        width: calc((100% - 2.4375rem) / 2);
        max-width: 21.5625rem;
    }
}

.resources-with-logos.resources-with-logos--patients {
    background: #fff;
    padding-top: 100px;
    padding-bottom: 100px;
}

.resources-with-logos.resources-with-logos--patients .container {
    max-width: 908px;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__headline {
    color: var(--Primary-Blue, #021F90);
    font-family: "DM Serif Display";
    font-size: 3.75rem;
    font-style: normal;
    font-weight: 400;
    line-height: 104%;
    margin: 0 0 50px;
    text-align: center;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logos {
    display: flex;
    justify-content: space-between;
    align-items: center;
    flex-wrap: wrap;
    max-width: 908px;
    margin: 0 auto;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo {
    display: flex;
    align-items: center;
    justify-content: center;
    padding: 0;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-image {
    padding-right: 20px;
    border-right: 1px solid rgba(0, 0, 0, 0.2);
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-image img {
    display: block;
    max-width: 100%;
    width: auto;
    height: auto;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo:nth-child(1) .resources-with-logos__logo-image img {
    width: 227px;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo:nth-child(2) .resources-with-logos__logo-image img {
    width: 349px;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    margin-left: 20px;
    text-decoration: none;
    flex: 0 0 auto;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link--card {
    margin-left: 0;
    gap: 20px;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link-icon-wrap {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    flex: 0 0 auto;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link-icon {
    width: 23px;
    height: 23px;
    display: block;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link-icon-circle,
.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link-icon-arrow {
    transition: fill 0.2s ease, stroke 0.2s ease;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo:hover .resources-with-logos__logo-link-icon-circle,
.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link:hover .resources-with-logos__logo-link-icon-circle,
.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link:focus-visible .resources-with-logos__logo-link-icon-circle {
    fill: #FFFFFF;
    stroke: #FF2E83;
}

.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo:hover .resources-with-logos__logo-link-icon-arrow,
.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link:hover .resources-with-logos__logo-link-icon-arrow,
.resources-with-logos.resources-with-logos--patients .resources-with-logos__logo-link:focus-visible .resources-with-logos__logo-link-icon-arrow {
    fill: #FF2E83;
}

.resources-with-logos.resources-with-logos--patients .description{
    font-size: 14px;
    line-height: 140%;
    text-align: justify;
    margin-top: 20px;
}

@media (max-width: 62rem) {
    .hero-section.hero-section--patients .hero-section__headline {
        text-wrap: pretty;
    }

    .resources-with-logos.resources-with-logos--patients .resources-with-logos__logos {
        justify-content: center;
        gap: 30px;
    }
    .three-box-content--patients::before {
        aspect-ratio: 1920 / 300;
    }
}

@media (max-width: 52.125rem) {
    .patients-page .two-columns-with-image {
        padding-top: 3.125rem;
        padding-bottom: 3.125rem;
    }

    .hero-section.hero-section--patients .hero-section__headline,
    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__headline,
    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__headline,
    .patients-page__content--patients .two-columns-with-image__headline,
    .two-columns-with-image--patients .two-columns-with-image__headline,
    .two-columns-with-image--more-choice .two-columns-with-image__headline,
    .two-columns-image--more-choice .two-columns-with-image__headline,
    .resources-with-logos.resources-with-logos--patients .resources-with-logos__headline,
    .patients-page__content h1,
    .patients-page__content h2 {
        font-size: 3rem;
    }
}

@media (max-width: 31.75rem) {
    .patients-page__content--patients .two-columns-with-image__content,
    .two-columns-with-image--patients .two-columns-with-image__content,
    .two-columns-with-image--more-choice .two-columns-with-image__content,
    .two-columns-image--more-choice .two-columns-with-image__content {
        padding-bottom: 3.125rem;
    }

    .two-columns--azenosertib,
    .two-columns-image--azenosertib-works {
        padding-top: 3.125rem;
        padding-bottom: 3.125rem;
    }

    .two-columns-image--azenosertib-works .two-columns-with-image__text {
        padding-bottom: 1.5625rem;
    }

    .three-box-content--patients {
        padding-top: 3.125rem;
        padding-bottom: 3.125rem;
    }

    .resources-with-logos.resources-with-logos--patients {
        padding-top: 3.125rem;
        padding-bottom: 3.125rem;
    }

    .three-box-content--patients .three-box-content__grid {
        flex-direction: column;
        flex-wrap: nowrap;
        align-items: stretch;
    }

    .three-box-content--patients .three-box-content__box {
        width: 100%;
        max-width: none;
        flex: 0 0 auto;
    }

    .hero-section.hero-section--patients {
        padding-top: 3.125rem;
        padding-bottom: 5.625rem;
    }

    .hero-section.hero-section--patients::after {
        height: 6.25rem;
    }

    .hero-section.hero-section--patients .hero-section__subtext {
        font-size: 1rem;
        text-wrap: pretty;
        margin-bottom: 0;
    }

    .hero-section.hero-section--patients .hero-section__headline,
    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__headline,
    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__headline,
    .patients-page__content--patients .two-columns-with-image__headline,
    .two-columns-with-image--patients .two-columns-with-image__headline,
    .two-columns-with-image--more-choice .two-columns-with-image__headline,
    .two-columns-image--more-choice .two-columns-with-image__headline,
    .resources-with-logos.resources-with-logos--patients .resources-with-logos__headline,
    .patients-page__content h1,
    .patients-page__content h2 {
        font-size: 2.5rem;
    }
}

@media (max-width: 26.875rem) {
    .hero-section.hero-section--patients .hero-section__headline,
    .two-columns--azenosertib.two-columns-with-image--offset-headline .two-columns-with-image__headline,
    .two-columns-image--azenosertib-works.two-columns-with-image--offset-headline .two-columns-with-image__headline,
    .patients-page__content--patients .two-columns-with-image__headline,
    .two-columns-with-image--patients .two-columns-with-image__headline,
    .two-columns-with-image--more-choice .two-columns-with-image__headline,
    .two-columns-image--more-choice .two-columns-with-image__headline,
    .resources-with-logos.resources-with-logos--patients .resources-with-logos__headline,
    .patients-page__content h1,
    .patients-page__content h2 {
        font-size: 2rem;
    }

    .hero-section.hero-section--patients .hero-section__subtext {
        font-size: 0.85rem;
        text-wrap: pretty;
    }
}

@media (max-width: 48rem) {
    .hero-section.hero-section--patients .hero-section__subtext {
        max-width: 100%;
        line-height: 110%;
        letter-spacing: 1.1px;
    }

    .resources-with-logos.resources-with-logos--patients .resources-with-logos__logo:nth-child(1) .resources-with-logos__logo-image img {
        width: 13.125rem;
    }

    .resources-with-logos.resources-with-logos--patients .resources-with-logos__logo:nth-child(2) .resources-with-logos__logo-image img {
        width: 17.1875rem;
    }
}

@media (max-width: 40rem) {
    /*
     * Mobile gutter system (patients page only):
     * - content keeps 1.5625rem side gutters
     * - decorative blocks can still bleed to viewport edge
     * - math uses media-relative positioning instead of hardcoded viewport offsets
     */
    .patients-page .patients-page__section-row .two-columns-with-image--more-choice .two-columns-with-image__media,
    .patients-page .patients-page__section-row .two-columns-image--more-choice .two-columns-with-image__media,
    .patients-page .patients-page__section-row .two-columns--azenosertib .two-columns-with-image__media,
    .patients-page .patients-page__section-row .two-columns-image--azenosertib-works .two-columns-with-image__media {
        width: 100%;
        max-width: none;
    }

    .patients-page .patients-page__section-row .two-columns-with-image--more-choice .two-columns-with-image__media,
    .patients-page .patients-page__section-row .two-columns-image--more-choice .two-columns-with-image__media {
        align-self: flex-end;
        width: min(100%, 21.75rem);
        max-width: 21.75rem;
        margin-right: 0;
    }

    .patients-page .patients-page__section-row .two-columns-with-image--more-choice .two-columns-with-image__media-inner,
    .patients-page .patients-page__section-row .two-columns-image--more-choice .two-columns-with-image__media-inner,
    .patients-page .patients-page__section-row .two-columns--azenosertib .two-columns-with-image__media-inner,
    .patients-page .patients-page__section-row .two-columns-image--azenosertib-works .two-columns-with-image__media-inner {
        margin-left: auto;
        margin-right: auto;
    }

    .patients-page .patients-page__section-row .two-columns-with-image--more-choice .two-columns-with-image__media-inner,
    .patients-page .patients-page__section-row .two-columns-image--more-choice .two-columns-with-image__media-inner {
        max-width: 21.75rem;
        margin-left: auto;
        margin-right: 0;
    }

    .patients-page .patients-page__section-row .two-columns--azenosertib .two-columns-with-image__media-inner,
    .patients-page .patients-page__section-row .two-columns-image--azenosertib-works .two-columns-with-image__media-inner {
        max-width: var(--patients-azenosertib-media-max);
    }

    /*
     * More choice:
     * block starts ~57.85% into the media and bleeds to viewport right edge.
     */
    .patients-page .patients-page__section-row .two-columns-with-image--more-choice .two-columns-with-image__media::after,
    .patients-page .patients-page__section-row .two-columns-image--more-choice .two-columns-with-image__media::after {
        right: calc(-1 * var(--patients-gutter));
        left: 57.85%;
    }

    /*
     * Azenosertib:
     * block bleeds to viewport left edge and ends 1.5rem before image right edge.
     */
    .patients-page .patients-page__section-row .two-columns--azenosertib.two-columns-with-image--image-left .two-columns-with-image__media::after,
    .patients-page .patients-page__section-row .two-columns-image--azenosertib-works.two-columns-with-image--image-left .two-columns-with-image__media::after {
        top: calc(-1 * var(--patients-azenosertib-block-top));
        bottom: calc(-1 * var(--patients-azenosertib-block-bottom));
        height: auto;
        left: calc(50% - 50vw);
        right: calc(
            50%
            - (min(100%, var(--patients-azenosertib-media-max)) * 0.5 - 4.625rem)
        );
    }
}

@media (max-width: 31.75rem) {
    .patients-page .patients-page__section-row .two-columns-with-image--more-choice .two-columns-with-image__media::after,
    .patients-page .patients-page__section-row .two-columns-image--more-choice .two-columns-with-image__media::after {
        left: calc(57.85% - 3.75rem);
    }
}
