@import url('https://fonts.googleapis.com/css2?family=DM+Sans:ital,opsz,wght@0,9..40,100..1000;1,9..40,100..1000&family=DM+Serif+Display:ital@0;1&display=swap');
@import url('https://fonts.googleapis.com/css2?family=DM+Sans:ital,opsz,wght@0,9..40,100..1000;1,9..40,100..1000&family=DM+Serif+Display:ital@0;1&family=Poppins:ital,wght@0,100;0,200;0,300;0,400;0,500;0,600;0,700;0,800;0,900;1,100;1,200;1,300;1,400;1,500;1,600;1,700;1,800;1,900&display=swap');


body {
    font-family: 'DM Sans', sans-serif;
}

/* Prevent long text links from overflowing narrow content containers. */
main a,
.site-footer a{
    overflow-wrap: anywhere;
    word-break: break-word;
}

h1, h2, h3, h4, h5, h6 {
    font-family: 'DM Serif Display', serif;
}

h2.hero-section__subtext {
    font-family: inherit;
    font-size: inherit;
    font-style: inherit;
    font-weight: inherit;
    line-height: inherit;
    letter-spacing: inherit;
    text-transform: inherit;
}
h1 span.dot{
    color: #FF2E83;
}

.top-background{
    height: 14px;
    background: #021F90;
}

.logo-img{
    position: relative;
}
.logo-img>img{
    position: absolute;
    top: -20px;
    right: 50px;
}

.hamburger-inner{
    background: #AC1AB8;
    width: 1.94rem;
    height: 3px;
}
.hamburger-inner:before, .hamburger-inner:after{
    background: #AC1AB8;
    width: 1.94rem;
    height: 3px;
}

:root{
    --full-width: 1920px;
}

.site-header{
    max-width: var(--full-width);
    margin: 0 auto;
}

@media (min-width: 1900px) {
    .site-header {
        width: 100%;
        max-width: 100%;
    }
}

header nav.navbar-expand-lg .navbar-nav .nav-link{
    font-size: 16px;
    color: #511861;
    padding: 0.5rem 25px 20px;
}

nav .dropdown-item.active, nav .nav-link.active{
    color: #FF0083 !important;
}
nav .dropdown-item.active, nav .nav-link.active{
    font-weight: 700 !important;
}

@media (hover: hover) and (pointer: fine) {
    nav .nav-link:hover{
        color: #FF0083 !important;
    }
}
.navbar{
    padding: 0;
}

nav .navbar-nav li{
    list-style-type: none;
}

nav .row.py-1{
    padding-bottom: 0 !important;
}

.card-link,
.hero-button{
    cursor: pointer;
    transition: color 0.3s ease;
}

.card-link .btn-icon circle,
.hero-button .btn-icon circle,
.card-link .btn-icon path,
.hero-button .btn-icon path{
    transition: fill 0.3s ease, stroke 0.3s ease;
}

.card-link:hover .btn-icon circle,
.card-link:focus-visible .btn-icon circle,
.hero-button:hover .btn-icon circle,
.hero-button:focus-visible .btn-icon circle
{
    fill: #fff;
    stroke: #ac1abb;
    stroke-width: 1px;
}
.card-link:hover .btn-icon path,
.card-link:focus-visible .btn-icon path,
.hero-button:hover .btn-icon path,
.hero-button:focus-visible .btn-icon path{
    fill: #ac1abb;
}

/*menu*/
/* Main menu item style */
.navbar-nav .nav-link {
    font-weight: 500;
    padding: 1rem 1.25rem;
    color: #4a0064;
    transition: color 0.3s ease;
}

.navbar-nav .nav-link:focus-visible,
.navbar-nav .nav-item.active > .nav-link {
    color: #ff2fa3; /* Bright pink for active/hovered item */
}

@media (hover: hover) and (pointer: fine) {
    .navbar-nav .nav-link:hover{
        color: #ff2fa3; /* Bright pink for hovered item */
    }
}

/* Dropdown menu wrapper */
ul.dropdown-menu {
    display: none;
    padding: 27px 34px 26px 36px;
    background: #EFF0F1;
    box-shadow: 5px 5px 9px 0 rgba(0, 0, 0, 0.06);
    text-align: center;
}

@media (min-width: 992px) {
    .navbar-nav>li:hover> .dropdown-menu {
        display: block;
    }
}

/* Dropdown items inside */
ul.dropdown-menu{
    text-align: left;
}
.dropdown-menu .dropdown-item {
    font-size: 16px;
    font-weight: 500;
    color: #511861;
    padding: 10px 0;
}

/* Hover effect for dropdown items */
.dropdown-menu .dropdown-item:hover,
.dropdown-menu .dropdown-item:focus {
    color: #ff2fa3;
    background: transparent;
}

/* Fix submenu arrow and behavior */
.dropdown-toggle::after {
    display: none;
}

.menu-submenu-toggle {
    display: none;
}

@media (min-width: 992px) {
    .navbar-expand-lg .navbar-nav .dropdown-menu.dropdown-menu-end{
        display: block;
        padding: 0;
        position: unset;
        box-shadow: none;
    }
    .navbar-expand-lg .navbar-nav .dropdown-menu.dropdown-menu-end:hover > .dropdown-menu {
        display: block;
        width: max-content;
    }

    #navbarResponsive ul.dropdown-menu .dropdown-item {
        text-transform: none !important;
    }
}

/* Responsive fix (optional) */
@media (max-width: 991.98px) {
    #navbarMobile .navbar-nav.main-menu-mobile {
        max-width: 250px;
        width: 100%;
    }

    #navbarMobile .dropdown-menu.show {
        display: block;
    }

    #navbarMobile .menu-submenu-toggle[aria-expanded="true"] + .dropdown-menu,
    #navbarMobile .menu-submenu-toggle.is-open + .dropdown-menu {
        display: block;
    }

    #navbarMobile .nav-item.dropdown {
        display: flex;
        align-items: center;
        justify-content: space-between;
        flex-wrap: wrap;
        width: 100%;
    }

    #navbarMobile .nav-item.dropdown > .nav-link {
        flex: 1 1 auto;
        min-width: 0;
        width: auto;
        padding-right: 0;
    }

    #navbarMobile .menu-submenu-toggle {
        display: inline-flex;
        align-items: center;
        justify-content: center;
        flex: 0 0 auto;
        width: 19px;
        height: 19px;
        margin-left: 13px;
        padding: 0;
        border: 0;
        background: transparent;
    }

    #navbarMobile .menu-submenu-toggle::before {
        content: "";
        display: block;
        width: 6px;
        height: 7px;
        background-image: url("../images/pink-caret.svg");
        background-repeat: no-repeat;
        background-size: contain;
        transform: rotate(90deg);
        transition: transform 0.2s ease-in-out;
    }

    #navbarMobile .menu-submenu-toggle[aria-expanded="true"]::before,
    #navbarMobile .menu-submenu-toggle.is-open::before {
        transform: rotate(-90deg);
    }

    #navbarMobile ul.dropdown-menu {
        position: static;
        flex: 0 0 100%;
        box-shadow: none;
        padding: 10px 40px;
        background: none;
        text-align: left;
    }

    #navbarMobile .dropdown-menu .dropdown-item {
        text-transform: none !important;
    }

    .dropdown-item {
        padding: 10px 15px;
    }
}

/*end menu*/


.search-btn{
    margin-left: 25px;
    margin-bottom: 15px;
}


/*footer */
.footer {
    background-color: #021F90;
    max-width: var(--full-width);
    margin: auto;
    background-size: contain;
    background-repeat: no-repeat;
    background-position: right bottom;
    background-image: url('../images/icons/Accent-rings-cropped.png')
}

.footer-content {
    max-width: 1300px;
    width: 100%;
    margin: 0 auto;
    padding: 50px;
    display: flex;
    justify-content: center;
    align-items: center;
}

.footer-left {
    flex: 1;
    min-width: 250px;
}

.footer-left .left-content{
    margin-top: 32px;
    margin-bottom: 15px;
}

.footer-left p {
    color: #FFF;
    font-size: 12px;
    line-height: 18px;
}

.footer-left p:first-child {
    margin-bottom: 10px;
}

.linkedin-icon img {
    width: 24px;
    height: 24px;
    padding: 2px;
    border-radius: 4px;
    margin-top: 10px;
}

.footer-right {
    display: flex;
    gap: 60px;
    flex-wrap: wrap;
    min-width: 300px;
}

.footer-right ul {
    list-style: none;
    margin: 0;
}

.footer-right ul li {
    margin: 8px 0;
}

.footer-right ul li a {
    color: #fff;
    text-decoration: none;
    font-size: 14px;
    line-height: 24px;
}
.footer-right ul li a:hover,
.footer-right ul li a.active{
    color: #fff!important;
}

.footer-right ul li a:hover{
    text-decoration: underline;
    text-decoration-color: #fff;
}

/*pipeline*/
.hero-pipeline-section {
    max-width: var(--full-width);
    margin: 130px auto 0;
    position: relative;
    background-color: white;
    text-align: center;
    height: 344px;
}

.hero-pipeline-section h1 {
    font-size: 60px;
    color: #021F90;
    margin-bottom: 12px;
}

.hero-pipeline-section h1 span {
    color: #ec008c;
}

.hero-pipeline-section p:first-of-type {
    font-size: 18px;
    font-weight: 500;
    line-height: 25px;
    letter-spacing: 1.98px;
    text-transform: uppercase;
    color: #0C9ECF;
    margin-bottom: 30px;
}

.hero-pipeline-section p:last-of-type {
    color: #313134;
    max-width: 683px;
    margin: 0 auto;
    font-size: 21px;
    line-height: 36px;
}

.pipeline_focused .status-info{
    display: flex;
    gap: 80px;
    align-items: center;
    margin-top: 33px;
    justify-content: end;
}
.pipeline_focused .status-info-item{
    display: flex;
    align-items: center;
    gap: 10px;
    font-size: 14px;
    font-weight: 400;
    line-height: 29px;
}
.pipeline_focused .status-info-item .dot{
    width: 20px;
    height: 20px;
    border-radius: 50%;
}
.pipeline_focused .status-info-item .dot.ongoing{
    background: #511861;
}
.pipeline_focused .status-info-item .dot.planned{
    background: #8C037B;
}

/* SVG Curve */
.curve {
    --svg-width: 1920px;
    --base-height: 185px;
    position: absolute;
    bottom: -1px;
    left: 0;
    width: 100%;
    overflow: hidden;
    line-height: 0;
    height: calc(var(--base-height) + (var(--svg-width) - 100vw) / 9.5);
}

.curve svg {
    display: block;
    width: 100%;
}

.curve path {
    fill: #F0F0EB;
}
/*end pipeline*/


/**/
.azenosertib{
    max-width: 1512px;
    width: 100%;
    margin: 179px auto 162px;
    position: relative;
}

.azenosertib .main-azenosertib .content-images img{
    border-radius: 0 24px 0 24px;
    width: 100%;
    height: 100%;
    object-fit: cover;
    object-position: left;
}

.azenosertib::before{
    content: "";
    position: absolute;
    top: 0;
    left: 0;
    width: 29%;
    height: 87%;
    /*aspect-ratio: 24 / 27;*/
    border-radius: 0 80px 0 0;
    background: rgba(217, 217, 217, 0.15);
    z-index: 0;
}


.azenosertib .main-azenosertib h2{
    max-width: 539px;
    color: #021F90;
    font-size: 60px;
    line-height: 53px;
    width: 100%;
    margin: 0 auto;
}

.azenosertib .main-azenosertib h2 .dot{
    color: #FF2E83;
}

.azenosertib .main-azenosertib .azenosertib-content{
    display: flex;
    gap: 64px;
    max-width: 1212px;
    width: 100%;
    margin: 60px auto 0;
    position: relative;
    z-index: 9;
    padding: 0 20px;
}
.azenosertib .main-azenosertib .content-images{
    position: relative;
    width: 29%;
    aspect-ratio: 168 / 197;
    align-self: self-start;
}
.azenosertib .main-azenosertib .content-images .vertical-label{
    position: absolute;
    left: -25px;
    top: 64px;
    transform: rotate(90deg) translateY(-50%);
    transform-origin: left top;
    font-size: 12px;
    letter-spacing: 2px;
}
.azenosertib .main-azenosertib .content-images .vertical-label span{
    color: #FF2E83;
}

.azenosertib .main-azenosertib .azenosertib-content-text{
    width: 66%;
}

.azenosertib .main-azenosertib .text-content .azenosertib-content p{
    color: #313134;
    font-size: 21px;
    line-height: 36px;
    margin-bottom: 50px;
}

.azenosertib .main-azenosertib .azenosertib-content-text{
    font-size: 21px;
}

.azenosertib .main-azenosertib .azenosertib-content-text .card-link{
    color: #511861;
    font-size: 21px;
    font-weight: 500;
    line-height: 17px;
    margin-top: 20px;
    display: flex;
    gap: 12px;
    align-items: center;
}

.card-link:hover,
.card-link:focus-visible,
.hero-button:hover,
.hero-button:focus-visible{
    color: #AC1AB8 !important;
}

.card-link:focus-visible,
.hero-button:focus-visible{
    outline: 2px solid currentColor;
    outline-offset: 4px;
    border-radius: 4px;
}


/* Combination Therapy */
.pipeline_focused {
    max-width: var(--full-width);
    width: 100%;
    margin: 0 auto;
    background: #F0F0EB;
}

.pipeline_focused  .container {
    max-width: 1254px;
    margin: auto;
    padding: 30px 20px 50px;
}

.pipeline_focused  .container .table-header{
    color: #313134;
    text-align: center;
    font-size: 21px;
    line-height: 36px;
    max-width: 950px;
    margin: 0 auto 52px;
    padding: 0 20px;
}



.pipeline_focused  .header {
    background-color: #021F90;
    color: #FFF;
    border-radius: 12px;

    display: flex;
    font-weight: 600;
    overflow: hidden;
}

.pipeline_focused .header div{
    font-family: Poppins, serif;
    font-size: 16px;
    font-weight: 600;
    line-height: 24px;
    flex: 1;
    min-width: 100px;

    display: inline-flex;
    padding: 12px 10px 12px 17.75px;
    align-items: center;
    border-right: 1px solid #FFF;
}
.pipeline_focused .header div:nth-child(2){
    flex: 2;
}


.pipeline_focused .header div:last-child{
    border-right: none;
}

.pipeline_focused .section-title {
    font-family: 'DM Sans', sans-serif;
    color: #021F90;
    font-size: 22px;
    font-weight: 700;
    line-height: 24px;
    margin: 36px 20px 11px;
}


.trial-block {
    display: flex;
    background-color: #f9f9f9;
}

/* Left fixed column */
.trial-block .trial-title {
    padding: 20px;
    display: flex;
    width: 15%;
    border-bottom: 1px solid #fff;
}
.trial-block .trial-title p{
    font-size: 16px;
    padding-right: 10px;
    font-weight: 500;
    line-height: 24px;
    align-self: center;
}


/* Center flexible area */
.trial-block .trial-parts {
    flex: 1;
    padding: 20px 24px;
    font-size: 14px;
    line-height: 1.5;
    width: 69.51%;
}

.trial-block .trial-parts .part-row {
    display: flex;
    align-items: center;
    margin-bottom: 24px;
}

.trial-block .trial-parts .part-row:last-child {
    margin: 0;
}

.trial-block .trial-parts .part-text {
    width: 38%;
    color: #000;
    font-size: 12px;
    line-height: 17px;
}
.trial-block .trial-parts .part-bar{
    width: 65%;
}

.trial-block .trial-parts .part-text p{
    margin: 0;
}

.trial-block .trial-parts .progress-bar {
    height: 20px;
    border-radius: 0 10px 10px 0;
    margin-left: 20px;
}

.trial-block .trial-parts .part-row:last-child .progress-bar{
    width: 55%;;
}

/* Right fixed column */
.trial-block .trial-status {
    width: 14.83%;
    display: flex;
    flex-direction: column;
}

.trial-block .status-block {
    text-wrap: pretty;
    margin: 0 5px;
    height: 50%;
    display: flex;
    align-content: center;
    align-items: center;
}

.trial-block .status {
    font-size: 14px;
}

.trial-block .status.completed {
    font-size: 14px;
    font-weight: 700;
    line-height: 14px;
    margin: 0;

}

.trial-status>div:first-child .status.completed {
    color: #FF2E83;
}

.trial-block .status {
    color: #000!important;
}

.trial-block .status.bold {
    color: #000;
    font-size: 14px;
    font-weight: 700;
    line-height: 20px;
    margin: 0;
}

.trial-block .status-sub {
    color: #6C6C73;
    font-size: 10px;
    font-weight: 700;
    line-height: 14px;
    letter-spacing: 0.3px;
}




/* Trial Block Base */
.randomized-block  {
    display: flex;
    background-color: rgba(217, 217, 217, 0.15);
}

/* Trial Title */
.randomized-block .trial-title {
    border-right: 1px solid #fff;
    display: flex;
    width: 15%;
    padding: 20px;
}

.randomized-block .trial-title p{
    max-width: 170px;
    font-size: 16px;
    font-weight: 500;
    line-height: 24px;
    align-self: center;
}

/* Middle */
.randomized-block .trial-parts {
    flex: 1;
    padding-right: 24px;
    width: 70%;
}

.randomized-block .part-row.single {
    display: flex;
    align-items: center;
}

.randomized-block .part-text {
    width: 38%;
    color: #000;
    font-size: 12px;
    line-height: 18px;
    margin: 22px 0 22px 24px;
}
.randomized-block .part-bar{
    width: 65%;
}



.randomized-block .part-text p{
    margin: 0;
}

/* Bar */
.randomized-block .progress-bar {
    height: 20px;
    background-color: #8C037B;
    border-radius: 0 10px 10px 0;
    margin-left: 20px;
}

/* Different bar sizes if needed */
.randomized-block .progress-bar.long,
.randomized-block .progress-bar.short
{
    width: 90%;
    max-width: 554px;
}


/* Status */
.randomized-block .trial-status {
    width: 14.88%;
    display: flex;
    align-items: center;
}

.randomized-block .status-block {
    text-wrap: pretty;
    font-size: 14px;
    font-weight: 700;
    line-height: 20px;
    display: flex;
    padding: 0 5px;
}

.randomized-block .status.bold {
    color: #000;
    font-size: 14px;
    margin: 0;
}

.randomized-block .status-sub {
    color: #6C6C73;
    font-size: 10px;
    line-height: 14px;
    letter-spacing: 0.3px;
}

.muir-study-block{
    background: #F9F9F9;
}

.muir-study-block .trial-status .success{
    color: #000;
    font-size: 14px;
    font-weight: 700;
    line-height: 120%;
    margin: 0;
}

.muir-study-block .trial-status .status-sub{
    color: #6C6C73;
    font-size: 10px;
    font-weight: 700;
    line-height: 14px;
    letter-spacing: 0.3px;
}

.muir-study-block .progress-bar.short{
    width: 18%;
}





.pipeline_focused .bottom-text{
    max-width: 1025px;
    margin: 61px auto 0;
    color: #313134;
    text-align: center;
    font-size: 21px;
    line-height: 36px;
}
/* end Combination Therapy*/

.mobile{
    display: none;
}

@media (min-width: 1512px) {
    .azenosertib::before{
        left: -205px;
        width: 43%;
    }
}
@media (min-width: 1212px) and (max-width: 1512px) {
    .azenosertib::before {
        width: clamp(
                18vw,
                calc(29vw - (1512px - 100vw) * 0.178),
                29vw
        );
    }
}

@media (min-width: 960px) {
    .search-btn{
        display: block !important;
    }
    .hamburger {
        display: none;
    }
    .d-lg-flex-custom {
        display: flex !important;
    }
}
@media (max-width: 1250px) {
    .azenosertib .main-azenosertib .content-images .vertical-label{
        display: none;
    }
}
@media (max-width: 1212px) {

    .azenosertib::before {
        width: 24.59vw;
        height: auto;
        aspect-ratio: 24 / 40;
    }

    .azenosertib .main-azenosertib h2{
        font-size: clamp(30px, 5vw, 60px);
        max-width: clamp(300px, 44vw, 522px);
    }
    .azenosertib .main-azenosertib .azenosertib-content-text{
        font-size: clamp(12px, 1.7vw, 21px);
    }
    .pipeline_focused .header div{
        font-size: clamp(12px, 1.33vw, 16px);
    }
}

@media (max-width: 1200px) {
    .hero-pipeline-section h1{
        font-size: 50px;
        line-height: 88%;
    }
    header nav.navbar-expand-lg .navbar-nav .nav-link{
        padding: 0.5rem 20px 15px;
    }
    .search-btn{
        margin-left: 10px;
    }

}

@media (max-width: 959px) {
    .logo-img>img{
        display: none;
    }
    header .navbar{
        padding: 18px 0 28px;
    }

    .hero-pipeline-section{
        padding: 0 15px;
        margin-top: 90px;
    }

    .azenosertib{
        margin: 100px auto;
    }
    .azenosertib .main-azenosertib .azenosertib-content-text p:first-child{
        margin-bottom: 10px;
    }
    .randomized-block .trial-title p{
        font-size: 14px;
    }
    header nav.navbar-expand-lg .navbar-nav .nav-link{
        padding-bottom: 0;
    }
    .navbar-nav .dropdown-menu{
        padding-top: 0;
        padding-left: 30px;
    }
}

@media (max-width: 767px) {
    .desktop{
        display: none;
    }
    .mobile{
        display: block;
    }
    .hero-pipeline-section{
        padding: 0 20px;
        margin-top: 61px;
        height: 290px;
    }
    .hero-pipeline-section h1{
        font-size: 40px;
        line-height: 35px;
    }
    .hero-pipeline-section p:first-of-type{
        font-size: 15px;
        line-height: 13px;
        letter-spacing: 1.68px;
    }
    .hero-pipeline-section p:last-of-type{
        line-height: 110%;
        letter-spacing: 1.1px;
    }

    .pipeline_focused .container .table-header{
        font-size: 19px;
        line-height: 32px;
    }



    .azenosertib{
        max-width: 430px;
        margin: 67px auto 76px;
    }
    .azenosertib::before{
        top: 100px;
        width: 80%;
        aspect-ratio: 24 / 29;
    }
    .azenosertib .main-azenosertib h2{
        font-size: clamp(30px, 10vw, 40px);
        max-width: 430px;
        padding: 0 20px;
        text-align: center;
        line-height: 35px;
    }
    .azenosertib .main-azenosertib .azenosertib-content{
        flex-direction: column;
        max-width: 430px;
        margin-top: 100px;
    }
    .azenosertib .main-azenosertib .content-images{
        width: 100%;
        aspect-ratio: auto;
    }
    .azenosertib .main-azenosertib .content-images img{
        border-radius: 0 24px 0 24px;
    }
    .azenosertib .main-azenosertib .azenosertib-content-text{
        line-height: 32px;
        width: 100%;
        font-size: clamp(16px, 4.59vw, 19px);
    }
    .azenosertib .main-azenosertib .azenosertib-content-text .card-link{
        font-size: clamp(16px, 4.59vw, 19px);
    }
    .pipeline_focused .bottom-text{
        font-size: 19px;
        line-height: 32px;
        padding: 0 20px;
        margin: 44px auto 0;
    }


    /*moblie schema*/
    .pipeline_focused .container{
        max-width: 430px;
        margin: 0 auto;
        padding: 76px 0 51px;
    }
    .pipeline_focused .mobile .section-title{
        margin-bottom: 45px;
    }
    .mobile .trial-block{
        flex-direction: column;
        background-color: #fff;
    }
    .mobile .trial-block .trial-title{
        width: 100%;
        padding: 30px 20px 12px;
    }

    .mobile .trial-block .trial-parts .part-row{
        flex-direction: column;
    }
    .mobile .trial-block .trial-parts .part-row:first-child{
        border-bottom: 1px solid #F0F0EB;
    }

    .mobile .trial-block .trial-parts .part-row:last-child{
        flex-direction: column;
    }

    .mobile .trial-block .trial-status,
    .mobile .trial-block .trial-parts,
    .mobile .trial-block .trial-parts .part-text,
    .mobile .trial-block .trial-parts .part-bar,
    .mobile .trial-block .trial-parts .part-bar,
    .mobile .randomized-block .trial-title,
    .mobile .randomized-block .trial-parts,
    .mobile .randomized-block .part-text,
    .mobile .randomized-block .part-bar,
    .mobile .randomized-block .trial-status{
        width: 100%;
    }
    .mobile .randomized-block .trial-title p{
        max-width: 100%;
        font-size: 16px;
    }


    .mobile .trial-block .trial-parts .part-bar{
        padding: 20px 0;
    }
    .mobile .trial-block .trial-parts .part-text{
        padding: 0 20px;
    }
    .mobile .trial-block .trial-parts .progress-bar,
    .mobile .trial-block .trial-parts .part-row:last-child .progress-bar{
        margin: 0;
    }
    .mobile .trial-block .status-block:last-child{
        margin-top: 0;
        margin-left: 40px;
    }
    .mobile .trial-block .trial-status{
        display: flex;
        flex-direction: row;
        margin-top: 32px;
        padding: 0 20px;
    }
    .mobile .trial-block .trial-status .status-title{
        width: 33%;
        font-size: 15px;
        font-weight: 700;
        color: #021F90;
    }
    .mobile .trial-block .trial-parts{
        padding: 24px 0 0;
    }
    .mobile .trial-block .part-row:first-child .status.completed{
        color: #FF2E83;
    }

    .pipeline_focused .mobile .header{
        width: 100%;
        border-radius: 0;
        margin-top: 32px;
    }
    .pipeline_focused .mobile .header div{
        padding-left: 22px;
    }
    .pipeline_focused .header div:nth-child(2){
        flex: 1;
    }
    .mobile .randomized-block{
        background: #F9F9F9;
        flex-direction: column;
        padding-bottom: 18px;
    }
    .mobile .randomized-block .trial-parts{
        padding-right: 0;
    }
    .mobile .randomized-block .part-row.single{
        flex-direction: column;
    }
    .randomized-block .progress-bar.long,
    .randomized-block .progress-bar.short
    {
        margin-left: 0;
    }
    .mobile .randomized-block .trial-title{
        padding: 30px 20px 12px;
    }
    .mobile .randomized-block .part-text{
        margin: 0;
        padding: 0 20px;
        line-height: 17px;
    }
    .mobile .randomized-block .trial-status{
        display: flex;
        margin-top: 32px;
        padding: 0 20px 25px;
        border-bottom: 1px solid #F0F0EB;
    }
    .mobile .randomized-block .trial-status .status-title{
        font-size: 15px;
        font-weight: 700;
        color: #021F90;
    }
    .mobile .randomized-block .trial-status .status-block:last-child{
        margin-top: 0;
        margin-left: 40px;
    }
    .mobile .randomized-block .part-bar{
        margin-top: 20px;
    }

    .footer-content{
        flex-direction: column;
        align-items: self-start;
        max-width: 414px;
        padding: 74px 32px 76px;
        gap: 42px;
    }
    .footer-content .footer-right ul li{
        margin: 40px 0;
    }
    .footer-content .footer-right ul li a{
        line-height: 20px;
    }

    .footer-content .footer-left .left-content{
        margin-bottom: 22px;
    }
    .footer-content .footer-left .social-icons a img{
        width: 40px;
    }
    .footer{
        background-image: url('../images/icons/footer-graphic2x.png')
    }
    .curve{
        --base-height: 200px;
    }
    .pipeline_focused .status-info-item{
        font-size: 12px;
    }
    .pipeline_focused .status-info{
        padding: 0 20px;
        gap: 40px;
    }
}
@media (max-width: 430px) {
    .curve{
        --base-height: 200px;
    }
}
@media (max-width: 390px) {
    .hero-pipeline-section h1{
        font-size: 30px;
    }
    .hero-pipeline-section p:first-of-type{
        font-size: 12px;
    }
    .hero-pipeline-section p:last-of-type{
        font-size: 16px;
        line-height: 28px;
    }
    .azenosertib .main-azenosertib .azenosertib-content{
        margin-top: 90px;
    }
    .footer-content .footer-right{
        gap: 25px;
    }
    .logo-img{
        padding-right: 0;
    }
    .logo-img+div{
        padding-left: 0;
    }
}
span.pink-dot {
  color: var(--Secondary-Pink, #FF2E83);
}

.text-link-with-icon {
    display: inline-flex;
    align-items: center;
    gap: 0.3125rem;
    color: var(--Neutral-Dark-Gray, #313134);
    font-family: "DM Sans";
    font-size: 1.3125rem;
    font-style: normal;
    font-weight: 400;
    line-height: 2.25rem;
    text-decoration: underline;
    text-decoration-skip-ink: none;
    text-decoration-thickness: from-font;
    text-underline-offset: 0.15em;
}

.text-link-with-icon::after {
    content: "";
    width: 1.25rem;
    height: 1.25rem;
    flex: 0 0 auto;
    background: url("../images/icons/purple-external-link.svg") center / contain no-repeat;
}

.text-link-with-icon:hover {
    text-decoration: none;
}
.text-link-with-icon:hover::after {
    background: url("../images/icons/white-external-link.svg") center / contain no-repeat;
}

.accordion-block .accordion-button {
    padding-left: 42px;
}

.accordion-block .accordion-button::before {
    content: "";
    display: block;
    position: absolute;
    top: 50%;
    left: 0;
    width: 18px;
    height: 18px;
    transform: translateY(-50%);
    background: url("../images/icons/white-plus.svg") center / contain no-repeat;
}

.accordion-block .accordion-button::after {
    content: none;
}

.accordion-block .accordion-button:not(.collapsed)::before {
    background-image: url("../images/icons/white-minus.svg");
}

.publication-single__article {
    padding-top: 80px;
    padding-bottom: 80px;
    padding-left: 25px;
    padding-right: 25px;
}

@media (max-width: 575px) {
    .publication-single__article {
        padding-top: 50px;
        padding-bottom: 50px;
    }
}